Showing posts with label prostate. Show all posts
Showing posts with label prostate. Show all posts

Saturday, May 17, 2008

Men’s Body Click Diet part 4

Benign Prostatic Hypertrophy and Prostate Cancer

Benign prostatic hypertrophy is an enlargement of the prostate that's called benign because it is not due to cancer cells. Still, the enlargement can be far from benign if it results in a lack of control over functions that we all take for granted, including urinating when you want to urinate and only then. A single urinary accident in front of your classmates in the first grade can constitute a major, unforgettable scar in one's childhood; a repeat performance, like that of my sixty-year-old patient while standing in line at the check-in counter at O'Hare Airport, is no joke either. Nor is `benign' the right word to describe the condition that underlies such loss of control. BPH may also involve getting up frequently at night to urinate, with the intense urgency to do so unfortunately combined with a disconcerting hesitancy of performance and a lack of reward in the volume of urine produced.

Although the symptoms of BPH can be severe, it is ironic that men with prostate cancer often have no symptoms. As they age, most men, on biopsy, show signs of prostate cancer. In fact, by the time they are in their eighties, nearly all men have prostate cancer, as defined by the typical cancerous appearance of cells under the microscope. Yet, because this particular cancer grows slowly and spreads infrequently, only a small percentage of men actually become sick or die from the disease. (A man's lifetime risk of dying from prostate cancer is a little less than three per cent.)`'

Diet Start

Given the low odds of illness or death from prostate cancer, it's confusing from a medical standpoint when a 60-, 70- or 80-year-old man has a prostate biopsy and is found to have cancer cells. Because the question of the actual malignancy of the condition — how likely it is that the cancer will grow quickly enough to cause problems — is difficult to resolve, it encourages a more aggressive approach to therapy than might otherwise be warranted. Since aggressive therapy frequently involves either removing testicles or taking female hormones, which can produce dramatic changes in a man's body, this is not a trivial question.

Natural therapies for treating or, more important, preventing illness are not usually studied in the same way as pharmaceuticals, because no one can patent a naturally occurring substance like flaxseed powder and make enough money to justify the enormous expense of carefully conducted, controlled and double-blinded studies. Still, the studies show that consuming soy protein and other isoflavone and lignan-containing foods reduces the risk of prostate cancer. And the cancer data suggest strongly — and there is abundant anecdotal evidence to support it — that the same hormonal environment that leads to the high incidence of cancer in older men inour culture, but not in Chinese and Finnish men, is also associated with the risk for prostatic enlargement.5

The simple strategy for preventing the range and frequency of prostate problems is to consume more soy protein, flaxseed powder and rye fiber. If you happen to be a regular bacon, ham or sausage and eggs kind of guy, I urge you to substitute the shake, with its soy protein and flaxseed powder, at least four days a week. It's good that you're eating protein at your morning meal and getting the lift you need at the beginning of the day, but what you're eating will not protect your health like soy protein and flaxseed. (If you don't have time for breakfast, see the section for travelers in the appendix, where you'll find a quick shortcut that will help you get your soy protein and flaxseed every day.

The Body Clock Diet and Heart Disease: It's not Just the Cholesterol

Coronary heart disease (CHD) is the number one killer of both men and women in the United States. Each year, more than five hundred thousand Americans die of heart attacks caused by CHD. Soy intake has been shown to lower cholesterol and decrease cardiovascular disease associated with high cholesterol. There is growing scientific evidence to support this; for example, one recent study showed that a diet high in soy protein reduced cholesterol by as much as 20 per cent. 6 Other research has demonstrated that soy protein lowers triglycerides and reduces the oxidation of LDL or 'bad' cholesterol, which contributes to blood vessel problems linked to cardiovascular disease? And flaxseed has also been shown to lower both total and LDL cholestero1. The Body Clock Diet, which includes daily intake of soy protein and flaxseed powder, ensures that you get this important protection.

But cholesterol is not the exclusive evil agent in heart disease. Some people, especially those with complicating conditions of diabetes, tobacco smoking and a strong family history of heart disease and obesity, carry cholesterol-related risks. But most people who have heart attacks and other complications of 'hardening of the arteries' have fairly normal cholesterol levels.

The tide of medical thinking is changing when it comes to heart disease. It looks as if issues related to carbohydrate excess, insulin resistance and homocysteine and its control by folic acid will take center stage away from cholesterol. 9 The benefits of substances like flaxseed and soy are not due solely to lowering cholesterol. Soy and flaxseed do indeed lower serum cholesterol, but they also modify carbohydrate and fat metabolism, further decreasing your cardiovascular risk. You don't have to be takingaim at your cholesterol to get benefits from soy, flaxseed and the Body Clock Diet.

Like many men, you may have a tendency not to think about your health, shrugging off warnings from your mother, spouse, doctor and children as well as newspapers and television programs that try to scare or educate you about activities that are dangerous to your well-being. Nor do you want to listen to me when I say that failure to adhere to basic circadian principles may eventually show up as something noticeably wrong with your health. But my advice is simple: there are some painless things you can do to reap what are potentially major rewards for your long-term health.

Men’s Body Click Diet part 3

What happened with my patient Brooks shows how this scenario plays out. It also reveals why I think that such mysterious and sometimes chronic inflammations of the prostate are usually not infections but instead have a lot to do with factors that are also related to abnormal growth or cancers of the prostate.

Brooks is a 50-year-old businessman whose previously dependable penis had become much less reliable with regard to its sexual responsibilities. At the same time he suffered from discomfort with urination, some hesitancy in starting his urinary stream and the need to get up at night to urinate more than once, which had been his previous custom. He was alarmed that whatever was going on represented some sort of permanent equipment failure. Told at first by both a general practitioner and a urologist that his prostate was 'pretty normal' and later that it was a 'little enlarged', he had undergone two courses of antibiotic treatment for nonspecific prostatitis. His symptoms improved while he was on the antibiotics but returned when he finished the medication.

I had a telephone consultation with him and after hearing him out and considering various possibilities, I suggested to him that he had 'some kind of mischief' with his prostate. This was a much softer diagnosis than that of nonspecific prostatitis. But it suggested a treatment that was aimed more at making his prostate happy than at trying to kill some unseen, unidentified and perhaps nonexistent germs.

Diet Start

The concept of trying to make some organ in your body happy seem, alien to a regular guy like Brooks. He shares with most people the medical notion that there is a specific treatment for every condition and that this treatment is not a strategy to make some part of your body happy. It did, however, make Brooks happy when I suggested that part of his therapy was at least daily efforts to encourage the emptying of his prostate and its tubing by provoking an ejaculation. This was contrary to the no-sex advice he had been given earlier, which seemed to me like the equivalent of telling someone with a bad cold not to blow his nose.

I offered Brooks a package of additional measures to make his prostate happy. These included daily doses of soy protein, flaxseed powder, flaxseed oil, zinc and an antifungal medicine. If you understand why I loaded my shotgun with such a diversity of remedies and how they all fit together, you will also see how I perceive that the whole range of prostate mischief from inflammation to cancer fits together.

I've already explained the soy protein and flaxseed powder. I also recommended an additional supplement of flaxseed oil. The prostate gland is one of the richest sources of the hormonelike substances that are made from omega-3 fatty acids, with which flaxseed oil is loaded. They are called prostaglandins, named for the very organ under discussion, because they were first isolated from fluids found in the prostate. (Soon after their discovery in prostatic fluids, they were found to be present in a wide variety of animal tissues of all kinds and not at all exclusive to the prostate, but the name stuck.) The use of fatty acids in flaxseed oil helps the prostate make prostaglandins. But the more important motive for a prescription of flaxseed oil was the strong likelihood that Brooks, like most people, was deficient in omega-3 oils. The flaxseed oil, then, was generally beneficial rather than a treatment aimed specifically at the prostate.

I recommended that Brooks take zinc because it helps the immune system fight off infections and control the body's inflammatory response to infection. Finally, I prescribed the antifungal medicine because of my consistent experience with other patients where I'd seen that an overgrowth of fungus germs, particularly yeasts, has a proclivity to bother people's reproductive systems. I have often found stubborn cases of prostate problems in men to be responsive to antifungal drugs.

But there's another, more important angle to the antifungal treatment Igave Brooks and the many other men I've treated in a similar way. In order for the isoflavones and lignans in soy protein and flaxseed powder to be transformed into the substances that beneficially modulate hormone chemistry, they must pass through the digestive tract, where they are changed by certain germs that live there. If the normal distribution of healthy flora has been disturbed so that there are too many bad germs and not enough good germs, the capacity of the intestinal flora to help hormone chemistry will be seriously impaired. Antibiotics are by far the most significant disrupter of intestinal germ populations. A single course of an antibiotic prescription can affect this balance for months or longer. My prescription of an antifungal medicine for Brooks was aimed at two overlapping targets. One was the possibility that a fungal infection was directly related to the prostate inflammation; the other was that his two courses of antibiotics had made him worse by causing a disturbance in his bowel germ population that would correct itself once the number of yeast germs living there was reduced.

Within ten days Brooks and his prostate were both happy. His equipment returned to reliable functioning and he has remained well since. He is as pleased as he is surprised. This is true for many men whose similar responses to simple changes in diet don't jibe with their expectation that I would have to treat them by calling out the big guns rather than coaxing their bodies back into balance. I'm confident that the remedies I suggested for Brooks worked because they were specifically connected to achieving a hormonal balance governed by a combination of factors related to his digestive flora and an intake of substances that made his prostate happy.

It's not a big step from consideration of acute problems, such as what Brooks had, to the more chronic problems of prostate enlargement andprostate cancer.

Tuesday, May 13, 2008

Men’s Body Click Diet part 2

What I'm giving you here is a chance to climb the ship's mast with me so that from its top we can see far over the horizon of medicine. The view from the masthead is based not so much on my daily activities as a practicing physician but on my mission to search the seascape of scientific research for courses that can help prevent my patients from developing prostate trouble. What I see from the top of the mast is a body of evidence that is solid enough to support these simple changes in behavior, especially considering that there's zero risk in consuming flaxseed and soy protein.

The best evidence is based on studies done in a couple of places in the world, where prostate troubles are rare. Solid epidemiological studies that show a lower incidence of prostate cancer in men consuming foods popular among Finns and Chinese — rye bread for Finns and soy for Chinese.2 And he has carried out elaborate chemical analyses and experiments to show which substances in these foods provide the protection.

For years before his research was done, it was assumed that the Finns' genetic history accounted for their lower incidence of prostate cancer. Most modern Finns come from a small number of people who migrated to that part of the world many years ago, so they are a rather distinct linguistic, racial and genetic group. It turns out, however, that it's not their genes but their diet that protects them against certain cancers. And the dietary factor that is most significant is a sourdough rye bread that is eaten by people consuming a traditional Finnish diet. This whole-grain, heavy- duty bread is made out of ground whole rye seeds without anything removed. The leavening is provided by lactobacillus (acidophilus) instead of yeast, which is used to leaven almost all bread consumed in other parts of the world. What's key is that the rye fiber contains lignans that modulate hormone chemistry and reduce the risk of reproductive cancers.

Diet Start

Eastern Europeans have traditionally used flaxseeds as a source of food and medicine. Flaxseed oil, which makes up about one-third of the weight of the seeds, has extremely healthy properties that also provide particular benefits for the prostate gland. But here we're talking about the fiber in the flaxseed. The best way to use the seeds is to grind them in a coffee mill. You can then consume the fine, fluffy powder as part of a shake or add it to a variety of other foods. Your aim is to eat a heaping tablespoon per day.

Besides rye and flaxseed, there are other foods that contain lignans. Some of the best sources include legumes (especially lentils, kidney, fava and navy beans), seeds (like sunflower seeds), seaweed, cereal brans and whole grains.

There is also a solid body of evidence supporting the role of soy protein in reducing the risk of prostate cancer. For example, research has shown that isoflavones, substances contained in soybeans, modify testosterone metabolism, decreasing the risk for both benign prostatic hypertrophy and prostate cancer.3 Incorporating soy protein in your diet doesn't require you to change what you eat, although it's fine to eat more tofu, miso and other soy products if you enjoy them. The simplest, quickest way to consume soy protein is by stirring soy protein isolate, a relatively tasteless substance, into some of the food you are already eating.

Foods like soybeans, flaxseed and rye contain information derived from phytonutrients, which keep animals in synchrony with the rhythm of the seasons and which have profound effects on our own reproductive systems.

Prostate Inflammation or Nonspecific Prostatitis

Your prostate gland usually doesn't speak to you until it's in some advanced state of trouble. When it does, it has only two voices. One is expressed through pain or difficulty with urination and the other is just plain pain, which is almost invariably felt in the midline of your body. The spectrum of difficulties includes inflammation, enlargement and cancer. While there are more or less pure representations of each one, the lines between them are often blurred. All three, but particularly enlargement and cancer, are addressed by the preventive measures included in the Body Clock Diet.

Let's start with inflammation, which is the medical term for some combination of redness, pain, swelling and heat that almost always accompanies infection but may also represent your body's reaction to noninfectious irritants or allergens. The flame of prostate inflammation is experienced as burning with urination. This is as much a result of inflammation of the tube through which the urine passes out of the penis (the urethra) as it is due to inflammation of the prostate, per se, which lies astride this tube, just beneath the bladder. Germs that infect the urethra, such as the gonorrhea germ, may ascend it and get into the prostate gland. There, the alkaline environment and blood supply, which are conducive to bacterial growth, make it much harder to treat the infection with antibiotics than, say, a sore throat, a boil or an uncomplicated pneumonia. Because the germs that infect the prostate are difficult to extract from apatient for a culture it has become a common practice for doctors to treat symptoms of prostate inflammation with antibiotics without knowing what germ, if any, might be there.

The diagnosis in this situation is 'nonspecific' prostatitis, which is a well- accepted medical term. But when you stop to think about it, it's peculiar. According to medical principles, when there is an infection, the perpetrator is almost always a particular germ. The prostate, like all internal tissues, is not likely to be infected by more than one germ at a time. The implication is that if there's an infection, it's quite specific. How then do we come up with the diagnosis 'nonspecific' prostatitis? It's a result of several factors; efforts to recover a germ are to no avail, the prostate acts as if there's an inflammation — with swelling, pain, difficulty urinating and sometimes cloudy or pussy urine — and antibiotics are at least temporarily soothing. But after antibiotic treatment, this problem recurs more often than other infections.

Men’s Body Click Diet part 1

In the summer the men had to cope with constant daylight, so they were missing the normal cues to go to bed. 'When it's daylight, even though it's midnight or one o'clock in the morning, you don't think of it as being the time to go to sleep,' says Dave. 'Your mind just says, hey, there's work to be done. I may be tired but I'm not recognizing the need for sleep because it's daylight.'

Already lacking the strong time-giving effects of light, the men could not set their body clocks by what they were eating, either. 'We had four meals a day. Two of them occurred at noon and midnight, the other two at six in the morning and six in the evening,' continues Dave. 'One of the difficulties in telling what time it was, was that the 6:00 a.m. and 6:00 p.m. meals were powdered scrambled eggs and the other two meals were stew. So if you woke up at six o'clock and went into the galley for a meal and you had powdered scrambled eggs, you didn't know whether you were having breakfast or dinner.'

Despite losing the signals that are normally provided by the cycle of light and dark, the timing of activity, intake of food, reasonable work shifts or even simple obedience to the clock, most of the men managed toget through without becoming acutely sick or injured. But some of them developed a condition they called Big Eye, in which they became stuck in a sleepless state. Almost everyone had duties that required exhausting physical labor, but even so, the men with Big Eye failed to sleep for days.

Diet Start

The men with Big Eye demonstrated that the body's flexibility is a double-edged sword. The loss of essential time givers easily disrupted their circadian rhythms, probably setting them up for health problems if they continued down that path. On the other hand, proper application of some fairly simple rules for circadian health could have rescued them. And the same rules can rescue you from a potentially perilous state of disorganization.

The Body Clock Prescription reinforces strong circadian rhythms; produces better sleep, enhanced moods, alertness and energy; and reduces the risk for reproductive cancers for everyone. In addition to these overall improvements in health and well-being, there are specific aspects of the diet that have a favorable impact on prostate health, a subject that provokes anxiety for many men.

Prostate Ailments: The 'Male Problem'

There is certainly cause for concern. Prostate ailments are an almost universal threat to men in Europe and North America. Among men in the United States, prostate cancer is the most common cancer; it is also the second leading cause of cancer death.' In addition, countless men suffer from other prostate problems. This phenomenon represents a kind of `male problem' corresponding roughly to what used to be called 'female problems', a much less specific collection of gynecological woes that were lumped under this heading in the mid-1900s. The notion of female problems embraced excessive menstruation, infertility, irregular periods,cramps, vaginal discharge and other kinds of medical mischief that women endure.

The male problem is more localized in the prostate gland, the part of the male reproductive system that secretes fluids that help transport sperm. Nevertheless, it is a fairly complicated picture, which includes inflammations of the prostate, a common condition known as benign prostatic hypertrophy (BPH) and prostate cancer.

What's more, prostate problems may lead you to needing a cystoscopy, where a narrow flashlight is inserted into the hole from which you pee until it arrives in your bladder. On the way, it passes through your prostate gland. Cystoscopy is a procedure that causes 'big eyes' in the bravest of men.

Besides cystoscopy, the other method often used to examine men with prostate complaints is digital rectal examination, in which the examiner can feel the profile of your prostate gland. (Digital refers to the doctor's finger, not his computer.) Both give much less information than you would expect to get from such relatively invasive procedures. Opening your mouth and saying Ah' discloses much more about your teeth, gums, tongue and throat than any rectal exam reveals about your prostate, unless you have a huge lump. Ultrasound, magnetic resonance imaging (MRIs) and computerized axial tomography (CAT) scans are necessary to get a good picture of what's happening to this gland, whose actual location on the floor of your pelvis seems mysterious to anyone who has not studied anatomy.

Diet and Prostate Health

If you look around you, especially as you get older and start hearing stories from men who have prostate trouble, you may wonder if there's something simple you can do to avoid it. I'm not talking about early detection, which is mentioned frequently these days. (Of course, most men's idea of early detection is that early next year or the year after would be just fine.) Nor am I saying that a good history, physical exam, measurements of prostate-specific antigen (PSA), a common blood test used to screen for prostate cancer and other indicators of your underlying health, prostate or otherwise, are not a good idea.

But you're misplacing your priorities if you go through those procedures without making some modest changes in your diet now to prevent troubles in the future. Most men who have a reasonably healthy personal and family medical history and who don't abuse themselves with excesses of drugs, tobacco and alcohol, other risky activities or excessive inactivity can probably remain free of obvious symptoms even if they don't implement all the points of the Body Clock Prescription. Some of these pointsare aimed at people who are trying to get out of serious medical trouble or who have risk factors that call on them to follow the diet very strictly.

Naturally, the more closely you follow the Body Clock Prescriptionthe better, but if you do nothing else, I urge you to consume soy protein and flaxseed powder daily to prevent prostate problems. By making these simple dietary changes and keeping your mind open to the possibility that fungal infection, intestinal overgrowth or allergy might have a hand in any prostate inflammation that is not otherwise easily diagnosed by a physician, you can go a long way toward avoiding the possibility of getting prostate cancer, as well as the other problems that frequently lead men to undergo cystoscopy.

... andjoyohoxing