Showing posts with label result. Show all posts
Showing posts with label result. Show all posts

Monday, March 10, 2008

Secrets of Athletes and weight control

For many sportsmen and -women, there are distinct advantages to maintaining an optimum ratio between body fat and lean body mass. Gymnasts, wrestlers, ballet-dancers and even jockeys strive for a low mass and a high strength-to-mass ratio. Fat tissue does not contribute to the generation of force or power and therefore, must be carried as 'dead' weight in activity involving strength or during any weight- bearing exercise (for example, in a sport like distance running). In fact, leanness is often a good predictor of performance. However, for many athletes, the 'quest for thinness' may become a pre-occupation.

An athlete may try to control body weight in one of several ways. Firstly, he or she may attempt to reduce and maintain a minimal body mass. This is commonly achieved in what amounts to chronic 'undernutrition'- which may in fact result in nutritional deficiencies. It has been shown that it is difficult to take in adequate amounts of certain vitamins and micronutrients - such as B12, folic acid, iron and calcium - when food energy intake is below 5 000 kilojoules (or 1 200 calories) per day.

In addition, chronic low energy (kilojoule) intake in endurance trained athletes will result in certain changes in metabolism, in order to 'spare' energy. An athlete with a low intake may be able to eat less to maintain his or her current body mass, than one with a normal intake. There may be changes in thyroid hormone function, menstrual irregularities in women and a decrease in 'resting metabolism' (see page 128). All these factors point to undernutrition.

Diet Start

Many athletes - particularly young ones - aim to increase their lean body mass or 'muscle bulk', so as to improve performance in some sport. This may involve special diets, protein supplements, drugs to stimulate appetite and anabolic drugs (such as the much-publicised anabolic steroids). A recent study of 76 local resistance-trained athletes revealed that they were taking in nearly 3 times the RDA (recommended dietary allowance) for protein, and then supplementing their diet with protein powders. These sportsmen would be expensive to feed - and, as already shown, their efforts would be to no avail.

It is important for an athlete to recognize that attempts at weight gain in order to increase muscle mass are only effective if accompanied by a resistance training programme which overloads the muscle. In addition, there is no strong scientific argument for supplementing the diet with protein to this extreme, and the long-term consequences on kidney function are as yet, unknown. Drugs, especially anabolic steroids, also have potentially harmful long-term side effects; in addition, they are illegal and generally considered as a 'cheating' method of improving performance.

Finally, many sports involve specific weight categories and certain athletes are regularly involved in 'making weight' prior to competition. Examples of these sporting activities include body building, boxing, martial arts, horse racing and collegiate wrestling. There has been a great deal of research into the weight control practices and dietary patterns of American collegiate wrestlers. In a study of over 700 high school wrestlers, it was estimated that these athletes lost between 2 and 12% of their body mass within 2-48 hours prior to competition. This 'weight cycling' was repeated between 5 and 30 times per season for each wrestler! Sixty-nine college wrestlers were surveyed and results revealed that the average weight a wrestler needed to lose to compete in a specific category was approximately 4,5 kg, 3 days prior to competition. All of those surveyed gained weight in the off-season, and tended to flucuate between 5 and 9 kg above competition weight each week during the season!

The rapid weight losses achieved by these athletes usually involve cutting down severely on food and fluid intake and 'thermal' methods designed to lose water through sweating (plastic suits, saunas, etc.). But studies show that this can be counterproductive, since a loss of as little as 2% of total body weight through dehydration causes reduced exercise and heat tolerance, which in turn may result in poor performance.

There is also evidence that athletes who regularly undergo 'weight cycling' or 'yo-yo' dieting and weight loss may experience long-term changes in growth and metabolism. Wrestlers who constantly have to 'cut weight' in order to compete have been shown to have a slower metabolic rate than those who can compete without losing mass. So, while leanness may be a good indicator of performance in some sports, the 'quest for thinness' itself may have a detrimental effect. Manipulating body weight through weight 'cycling' may also result in long-term changes in metabolism; the athlete should rather strive for a balance in weight control which will improve his or her performance in the long-term.

It is unlikely that manipulating food intake or a single isolated nutrient will lead to enhanced performance on its own. An overwhelming number of studies have shown that supplementing a balanced diet, containing sufficient protein, vitamins and minerals has no benefit on athletic performance. A consistent and well planned training programme is still the most effective way of improving athletic performance. However, good nutrition supports the training programme in ensuring optimal performance, and sound nutritional practices will allow the athlete to achieve his or her potential.

Friday, February 29, 2008

How food affects drugs

In order to work properly, drugs must be present in the correct amounts at the receptor sites of the cell membranes. A number of factors can affect the way in which a drug works and, therefore, its effect on the body. Food is one of the most important of these factors. It can affect the absorption of a drug, its movement through the blood, its metabolism and its excretion.

Food and drug absorption

When drugs are taken orally, their absorption is influenced in different ways by the presence of food in the digestive tract. For example, food causes increased secretion of hydrochloric acid (HCl) in the stomach which can result in the destruction of some penicillin antibiotics that are taken by mouth. For this reason, penicillin should always be taken 1 hour before or 3 hours after meals.

Calcium in milk and dairy products tends to bind with tetracycline antibiotics to form non-absorbable compounds, with the result that the drug is lost in the stool. This means that these foods should not be eaten at the same time or within a few hours of taking the medication. However, the instruction 'Not to be taken with milk products' which sometimes appears on medicine labels can be misleading as it does not mean that you cannot consume any milk products while you are on the medication.

Diet Start

Iron salts (such as ferrous sulphate) can also bind with tetracycline antibiotics and result in the loss of the antibiotic. Therefore, anyone using an iron supplement as well as a tetracycline should take them at least two hours apart.

On the other hand, the absorption of some drugs can be increased when they are taken with foods. For example, foods with a high fat content increase the absorption of Griseofulvin, an antibiotic and antifungal drug. Iron supplements are also absorbed better when they are taken with vitamin C or foods rich in vitamin C, such as orange and guava juice. Interestingly, although some drugs (such as aspirin) are absorbed better on an empty stomach, they should nevertheless be taken with food - or at least milk - because of their irritating effect on the stomach lining.

Food and drug metabolism

Certain reactions inside the body can chemically change a drug (`metabolize' it) so that it is quite a different compound by the time it leaves the bloodstream. For example, some drugs combine with body proteins as they move through the bloodstream, which has the effect of preventing these drugs from entering the cells where they were intended to act. Others are broken down into smaller chemical components by the liver, the kidneys and the digestive tract. The metabolism of specific drugs can be influenced by the following in food: protein content, alcohol content, charcoal broiling, certain types of vegetables, caffeine intake, dietary fibre and the times food is eaten in relation to drug intake.

Food and the excretion of drugs

When metabolized by the body, some food alters the pH of the urine making it either more or less acidic - which in turn affects the excretion of drugs and therefore, the duration of their effects. For example, if excretion is decreased, more of the drug will be reabsorbed into the blood and its effects will be prolonged.

As an illustration, vitamin C makes the urine more acidic, thereby reducing the excretion of acidic drugs like phenobarbital and aspirin. When taking an antibiotic for a urinary tract infection, it is beneficial to acidify the urine, because this will result in decreased excretion of the antibiotic.

What drugs should you take when?

In order to minimize the adverse effects of foods on drug absorption, metabolism and excretion, the timing of drug administration in relation to food intake is very important. This is why it is essential to adhere to any such instructions which may accompany a prescribed drug. For example:

  • If rapid absorption of the drug is desired, the doctor/pharmacist may specify on the prescription that the drug should be taken before meals.
  • Drugs that irritate the stomach (such as indomethacin, phenobarbitone) should be taken when the stomach is 'cushioned' with food. In this case, the prescription should specify that the drug is to be taken after (or in the middle of) a meal.
  • Fat-soluble drugs should not be taken with a fatty meal, since the medication will be absorbed with the fat content in the food; because fat is digested slowly, the drug may not be absorbed into the bloodstream as rapidly as it should be.
  • Acetylsalicylic acid, Bisacodyl, Erythromycin and tetracyclines should not be taken with milk (see above).
  • Ampicillin, Cloxacillin and Erythromycin-based drugs, as well as stearate and Penicillin G should not be taken with fruit juices or carbonated beverages.

... andjoyohoxing